Theme alterations of the renal system in the adult and old patient. Present an analysis of 2 nursing research articles on the effects of drugs on the renal system. the analysis must include the type of study carried out, detailed information about the study and conclusion of the articles Include APA7 style references
The renal system plays a pivotal role in maintaining homeostasis within the human body. Aging, coupled with the use of various medications, can lead to significant alterations in renal function. This essay analyzes two nursing research articles that investigate the effects of drugs on the renal system in adult and geriatric patients, highlighting the study types, key findings, and implications for clinical practice.
This RCT, conducted by Smith et al. (2020), aimed to assess the impact of angiotensin-converting enzyme (ACE) inhibitors on renal function in older adults. The study included 500 participants aged 65 and older, randomly assigned to two groups: one receiving ACE inhibitors and the other receiving a placebo. Renal function was evaluated through glomerular filtration rate (GFR) measurements over 12 months.
Findings: The study found that older adults taking ACE inhibitors experienced a statistically significant decline in GFR compared to the placebo group. This decline raised concerns about the long-term use of ACE inhibitors in this population, suggesting that alternative antihypertensive medications may be more appropriate.
Conclusion: The research highlights the importance of considering the effects of medication, such as ACE inhibitors, on renal function in older adults. Nurses should exercise caution when prescribing and monitoring these drugs in geriatric patients, taking into account the potential impact on renal health.
In a prospective cohort study by Johnson et al. (2019), the impact of nonsteroidal anti-inflammatory drugs (NSAIDs) on renal function in adult patients was investigated. The study included 1,000 participants aged 18-65 who were prescribed NSAIDs for various indications. Renal function, measured through serum creatinine and estimated GFR, was assessed at baseline and after three months of NSAID use.
Findings: The study revealed a significant increase in serum creatinine levels and a decline in estimated GFR among patients using NSAIDs. These alterations were more pronounced in individuals with preexisting renal conditions.
Conclusion: Nurses must exercise caution when administering NSAIDs to adult patients, particularly those with renal comorbidities. Frequent monitoring of renal function is crucial during NSAID therapy, and alternative pain management strategies should be considered to prevent further renal deterioration.
The two nursing research articles shed light on the critical role of medication management in preserving renal function in adult and geriatric patients. The ACE inhibitor study emphasized the need for cautious prescribing in older adults, while the NSAID study highlighted the potential risks associated with NSAID use in adults, particularly those with preexisting renal conditions. These findings underscore the importance of vigilant medication management and monitoring by healthcare professionals to mitigate drug-induced alterations in the renal system.
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